搴旂敤
搴旂敤
搴旂敤
搴旂敤
瀛樺湪浜庤娑蹭腑鐨勫惊鐜偪鐦ょ粏鑳?circulating tumor cell,CTC)鍦ㄧ檶鐥囩殑澶嶅彂涓庤浆绉讳腑鍙戞尌閲嶈浣滅敤,鍥犳瀵瑰惊鐜偪鐦ょ粏鑳炵殑鎹曡幏宸叉垚涓哄綋鍓嶇檶鐥囩爺绌剁殑鍏抽敭闂銆傛姉浣撲緷璧栨€у厤鐤鐝犳崟鑾稢TC鐨勬柟娉曞叿鏈夋搷浣滅畝渚裤€佸揩鎹风瓑鐗圭偣,浣嗗瓨鍦ㄦ牱鏈噺闇€姹傚ぇ鍜屽埗澶囨垚鏈槀璐电瓑闂銆傛嫙閲囩敤涓€绉嶆柊鍨嬬鐝犫€旂瓑绂诲瓙浣撲慨楗扮殑鐑３姘寲閾佺撼绫崇鐝?graphene-coated iron nitride magnetic beads,G@FeN-MB)寮€灞曟崟鑾疯偤鐧屽惊鐜偪鐦ょ粏鑳炵殑鍒濇鐮旂┒銆侴@FeN-MB鐢卞灞傜煶澧ㄧ儻鍖呰,鍐呮牳涓烘爱鍖栭搧,涓庡父鐢ㄧ殑姘у寲閾佸唴鏍哥浉姣斿叿鏈夋洿寮虹殑纾佸搷搴旀€с€傜煶澧ㄧ儻浣滀负纾佺彔鍖呰澹冲眰,鐩告瘮甯傞潰涓婄鐝犲父鐢ㄧ殑SiO2澹冲眰鍏锋湁鏇翠綆鐨勮川閲忋€佹洿楂樼殑绋冲畾鎬у拰鏇村ソ鐨勭敓鐗╃浉瀹规€с€傚皢姘ㄥ熀鐑３姘寲閾佺鐝犱笌缇у熀鐑３姘寲閾佺鐝犲垎鍒€氳繃鐩存帴鍚搁檮娉曞拰纰充簩浜氳兒娉曞埗澶?绉嶉摼闇変翰鍜岀礌纾佺彔,骞跺伓鑱擟TC琛ㄩ潰鏍囧織鐗╀笂鐨粏鑳為粡闄勫垎瀛?epithelial cell adhesion molecule,EpCAM)鐨勬姉浣撳埗澶囨皑鍩哄厤鐤鐝?amino immuno magnetic bead,AIMB)涓庣晶鍩哄厤鐤鐝?carbaxylic immunomagnetic bead,CIMB)銆傜粨鏋滄樉绀?2绉嶅厤鐤鐝犲潎鍙崟鑾稟549缁嗚優,AIMB鐨勬崟鑾锋晥鐜囩暐楂樹簬CIMB;涓轰簡妯℃嫙CTC鎹曡幏鐜,鍙栧仴搴蜂汉琛€涓嶢549缁嗚優娣峰悎鍒跺涓嶅悓娴撳害鐨勭粏鑳炴贩娑?骞跺埄鐢ㄦ崟鑾锋晥鐜囨洿楂樼殑AIMB鎹曡幏浜鸿A549缁嗚優,璁＄畻琚崟鑾风殑A549鍙婃崟鑾锋晥鐜?缁撴灉鏄剧ず,AIMB鎹曡幏鏁堢巼浠?6.25%~81.50%涓嶇瓑銆傜爺绌剁粨鏋滆瘉鏄庝簡鍩轰簬G@FeN-MB鍒跺鍏嶇柅纾佺彔鏂规硶鐨勫彲琛屾€?寰楀埌鐨凙IMB鍙互鐢ㄤ簬鑲虹檶CTC鍒嗛€?灞曠幇鍑哄叾搴旂敤浜庝复搴婄爺绌剁殑鍓嶆櫙銆?..
搴旂敤
搴旂敤
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