鏂规璇︽儏锛欬/div>

澶嶆潅娉ㄥ皠鍓備箣鑴傝川浣撶殑琛ㄥ緛涓庤В鍐虫柟妗圏/span>

鑴傝川浣撶矑寰勬帶鍒剁殑閲嶈鎬?/span>

绾崇背鑴傝川浣掽/span>(nanoliposomes)鏄竴绉嶅叿鏈夌被缁嗚優鑶滅７鑴傚弻鍒嗗瓙灞傜殑绾崇背鍥婃场浣擄紝鍥犱负纾疯剛灞備笌缁嗚優鑶滅殑缁撴瀯绫讳技锛屽彲浠ヤ笌缁嗚優鑶滆瀺鍚堬紝浠庤€屽皢鑽墿閫佸叆缁嗚優鏍镐腑銆傝剛璐ㄤ綋杞戒綋鐨勯噴鑽満鍒讹紝浣垮叾涓嶄絾鍙互澧炲姞鑽墿婧惰В搴︼紝杩樺叿鏈夋綔鍦ㄧ殑缂撻噴鎴栭澏鍚戠壒鎬э紝骞垮彈鐮斿彂浜哄憳鐨勯潚鐫愶紝鍏ㄧ悆鑼冨洿鍐呭凡鏈堻/span>10浣欑娉ㄥ皠鐢ㄨ剛璐ㄤ綋浜у搧鑾锋壒涓婂競銆侟/span>

绾崇背鑽墿涓庡叾浠栬嵂鐗╀竴鏍凤紝蹇呴』鍏锋湁瀹夊叏鎬с€佸彲鎺ф€т笌鏈夋晥鎬э紝鏈夋晥鎬ф槸绾崇背鑽墿瀹炵幇鐤剧梾娌荤枟鐨勫熀纭€銆傝剛璐ㄧ撼绫虫敞灏勫墏缁忕粰鑽湪浣撳唴杩愯浆鏃讹紝闇€瑕佸厠鏈嶅閲嶇敓鐞咟/span>/鐥呯悊灞忛殰锛屾墠鑳藉畨鍏ㄥ埌杈鹃澏鐐瑰彂鎸ユ不鐤椾綔鐢紝鍦ㄥ彂鎸ュ叾鑽晥鍓嶉渶瑕佸厠鏈嶈娑层€佺粍缁囥€佺粏鑳炲拰缁嗚優鍣ㄧ瓑澶氶噸灞忛殰銆侟sup>[1]閫氳繃璋冩帶绾崇背鑽墿鏈韩鐨勭墿鐞嗗寲瀛︽€ц川锛屽绾崇背鑽墿鐨勫ぇ灏忋€佸舰鐘躲€佽〃闈㈢數鑽风瓑锛屼竴瀹氱▼搴︿笂鑳藉鍏嬫湇鑽墿閫掗€侀殰纰岦/strong>銆侟sup>[^2]

鐩告瘮浜庝紶缁熸敞灏勫墏锛岃剛璐ㄤ綋鍏锋湁闈跺悜浣滅敤锛屽彲鍑忚交鑽墿鐨勬瘨鍓綔鐢紝鏈轰綋鍣ㄥ畼瀵逛笉鍚岀矑寰勫井绮掔殑闃荤暀鑳藉姏涓嶅悓锛屽彲閫氳繃鑴傝川浣撴敞灏勫墏鐨勭矑寰勬帶鍒迭/strong>瀹炵幇鑽墿琚姩闈跺悜鏁堟灉銆侟sup>[3]鑴傝川浣撶矑寰勫皬浜嶞/span>50nm鏃朵竴鑸兘鑳藉闈跺悜鑷宠劸缁勭粐锛涘湪50~100nm鏃惰兘闈跺悜鑷宠倽缁勭粐锛涘湪0.1~0.2渭m鏃惰兘澶熼澏鍚戣嚦鑲濈粍缁囪倽宸ㄥ櫖缁嗚優鐨勬憾閰朵綋锛涘湪7~12渭m鏃跺彲琚偤缁勭粐缁嗚優鎽勫彇锛涳紴12渭m鏃惰兘澶熻姣涚粏琛€绠′笂鐨粏鑳炴憚鍙栬繘鑰屽埌杈捐嵎鐦ょ粍缁囧唴锛涳紴15渭m鏃惰兘琚偁绯昏啘鍔ㄨ剦绛夎绠′笂鐨粏鑳炴憚鍙朁sup>[4]銆侟/span>

鑴傝川浣撶殑绮掑緞鐩存帴褰卞搷鑽墿鐨勯噴鏀俱€佺敓鐗╁埄鐢ㄥ害銆佽浇鑽噺銆侀澏鍚戞€х瓑锛屽湪鍒跺鏃跺簲鎺у埗绮掑瓙鐨勫ぇ灏忥紝鑾峰緱杈冪獎涓斿潎鍖€鐨勭矑搴﹀垎甯冦€侟/span>

濂ユ硶缇庡槈骞冲彴鎻愪緵鏁村鐨勮剛璐ㄤ綋鐨勮〃寰佸強 瑙ｅ喅鏂规锛屽彲鐢ㄤ簬蹇€熻瘎浼般€佷紭鍖栬剛璐ㄤ綋鐨勯厤 鏂瑰拰宸ヨ壓锛歅SI楂樺帇寰皠娴佸潎璐ㄦ満瀵硅剛璐ㄤ綋杩涜 鍒跺鍜岀矑寰勬帶鍒躲€丯icomp绮掑害鍒嗘瀽浠垎鏋愬钩鍧 绮掑緞鍙奪eta鐢典綅鐨勬娴嬨€丄ccuSizer棰楃矑璁℃暟鍣 鍒嗘瀽澶х矑瀛愭祿搴︼紝Lumispoc棰楃矑璁℃暟鍣ㄥ垎鏋愬皬绮掑瓙娴撳害銆丩um绋冲畾鎬у垎鏋愪华蹇€熷垎鏋愯剛璐ㄤ綋鐨 绋冲畾鎬э紝Entegris-ANOW婊よ姱杩囨护鏉傝川鍙婂ぇ棰楃矑銆

鑴傝川浣撳埗澶囨祦绋嬫杩?/span>

鍦ㄨ剛璐ㄤ綋鐨勫埗澶囨柟娉曚腑鏈夊绉嶅埗澶囨柟娉曪紝浼犵粺鐨勬柟娉曞锛氳杽鑶滄按鍖栨硶銆佹憾鍓傛敞鍏ユ硶銆侀€嗗悜钂稿彂娉曠瓑銆傝繖浜涙柟娉曞嚑涔庨兘鏄厛灏嗚剛璐ㄦ憾瑙ｅ湪鏈夋満婧跺墏涓紝鐒跺悗鍐嶅幓闄ゆ湁鏈烘憾鍓傘€傚彟澶栵紝涔熸湁澶ч噺鐨勯潪浼犵粺鍒跺鏂规硶鐢ㄤ簬鐮旂┒锛屽瓒呬复鐣屾祦浣?supercritical fluid, SCF)銆佸井娴佷綋鎶€鏈€佸喎鍐诲共鐕ユ硶銆傛澶勶紝浠嬬粛涓€绉嶈剛璐ㄤ綋鐨勫埗澶囨祦绋嬶紝瑙佸浘1锛岄€氳繃浼犵粺鏂规硶鍒跺绮掑緞姣旇緝澶х殑绮楄剛璐ㄤ綋锛屽湪闄ゅ幓鏈夋満婧跺墏鍚庯紝鍐嶉€氳繃寰皠娴佸潎璐ㄧ殑鏂瑰紡杩涗竴姝ラ檷浣庣矑寰勫強杩涜鏁寸矑锛涜€屽悗閫氳繃瓒呮护杩涜绾寲锛孅/span>寰楀埌绮掑緞鍧囦竴銆佹弧瓒充娇鐢ㄥ畨鍏ㄨ姹傜殑鑴傝川浣撱€傝剛璐ㄤ綋鐨勫钩鍧囩矑寰勫拰绮掑害鍒嗗竷鏄剛璐ㄤ綋鑽搧鍏抽敭璐ㄩ噺鐗规€э紝鏄捐憲褰卞搷鍏朵綋鍐呰涓恒€傛憾瑙ｇ７鑴傚彲鑳介渶瑕佺敤鍒版瘨鎬ф瘮杈冨ぇ鐨勬湁鏈烘憾鍓傦紝婧跺墏娈嬬暀闇€瑕佺鍚圛CH鐩稿叧瑙勫畾锛岄櫎鍘诲彲鑳藉瓨鍦ㄥ洶闅俱€傝秴婊ゆ槸褰卞搷绮掑緞鍜屾憾鍓傛畫鐣欑殑鍏抽敭宸ヨ壓锛屼篃鏄揪鍒版帶鍒剁殑鏈€鍚庝竴姝ュ伐鑹恒€侟sup>[5]

鍥? 鑴傝川浣撳埗澶囦笌琛ㄥ緛娴佺▼鍥近/span>

鑴傝川浣撶矑搴︽帶鍒迭/span>

鑴傝川浣撶粰鑽郴缁熷睘浜庨潪鍧囩浉鐑姏瀛︿笉绋冲畾绯荤粺锛岃剛璐ㄤ綋鍦ㄥ埗澶囪繃绋嬩腑锛岃嫢绮掑緞澶у皬鍙婂垎甯冧笉鍚堟牸锛屽垯浼氬奖鍝嶄骇鍝 鍚庣画璐ㄩ噺闂銆傜矖鑴傝川绮掗渶瑕佺粡杩囬珮鍘嬪潎璐ㄦ垨寰皠娴佽繘琛屾暣绮掞紝鑰屽悗杩涜瓒呮护绾寲锛屽緱鍒扮矑寰勫潎涓€鐨勮剛璐ㄤ綋銆傞珮鍘嬪井 灏勬祦鍧囪川鏈哄叿鏈夊ぇ瑙勬ā銆佽繛缁寲鐢熶骇绛夌壒鐐癸紝閫氳繃楂橀€熸挒鍑汇€佸壀鍒囦笌绌虹┐浣滅敤杈惧埌鍧囪川涓庣粏鍖栫殑鐩殑锛岀幇宸叉湁鐢ㄤ簬鍒 澶囬樋绯栬嫹銆佷腑閾捐剛鑲吀銆佽尪澶氶厷鍙婄淮鐢熺礌C绛夌撼绫宠剛璐ㄤ綋鐨勫疄渚嬨€侟/span>[6]

楂樺帇寰皠娴佸潎璐ㄦ満 PSI-20楂樺帇寰皠娴佸潎璐ㄦ満锛堝皬璇曞吋涓瘯鍨嬶級閲囩敤鍥哄畾 缁撴瀯鐨勫潎璐ㄨ厰锛岄€氳繃鐢垫恫浼犲姩鐨勫鍘嬪櫒浣跨墿鏂欏湪楂樺帇浣 鐢ㄤ笅浠ユ瀬澶х殑閫熷害娴佺粡浜や簰瀹硅厰鐨勫井绠￠€氶亾锛岀墿鏂欐祦鍦 姝よ繃绋嬩腑鍙楀埌楂樺壀鍒囧姏銆侀珮纰版挒鍔涖€佺┖绌存晥搴旂瓑鐗╃悊浣 鐢紝浣垮緱骞冲潎绮掑緞闄嶄綆銆佷綋绯诲潎涓€绋冲畾锛岀敱姝よ幏寰楃悊鎯 鐨勫潎璐ㄣ€佸垎鏁ｃ€佸幓鍥㈣仛鐨勭粨鏋溿€侟/span> 鈼鏈€楂楛/span>2069 bar鐨勫潎璐ㄥ帇鍔涳紝鏈€楂樺鐞嗛噺20L/h锛圏/span>PSI- 20锛 鈼閲囩敤鐗规畩璁捐Y鍨嬭厰锛屽幓闄ゅ熬绔ぇ棰楃矑鏁堟灉浣筹紝鐗╂枡 鐨勬贩鍚堟洿鍧囦竴锛屽鐞嗘晥鐜囬珮銆 鈼灞忔樉鐣岄潰锛屾暟鎹彲婧簮锛氭敮鎸佹暟鎹鍑鸿瀹氬帇鍔涘強瀹 鏃跺帇鍔涖€佺洃娴嬬偣娓╁害銆佸疄鏃舵祦閲忋€佹椂闂寸瓑銆侟/span> 鈼閰嶇疆K鍨嬬儹鐢靛伓锛氬彲鐢ㄤ簬瀹炴柦鐩戞祴鏂欐恫娓╁害銆 鈼浣庡櫔闊筹細杩愯闊抽噺浣庝簬70鍒嗚礉锛屽伐浣滅幆澧冨弸濂藉瀷銆侟/span>

骞冲潎绮掑緞涓嶞/span>Zeta鐢典綅妫€娴婞/span>

鑴傝川浣撶悊鍖栨€ц川璇勪环閫氬父鍖呮嫭绮掑緞澶у皬鍙婂垎甯冨潎鍖€绋嬪害銆佺ǔ瀹氭€у強鍖呭皝鐜囩瓑鏂归潰銆傜矑寰勫ぇ灏忓強鍒嗗竷闄や笌鍏跺寘灏佺巼鍙婄ǔ瀹氭€ф湁鍏冲锛屽悓鏃跺杞借嵂鑴傝川浣撶殑娌荤枟鏁堟灉鏈夌洿鎺ョ殑褰卞搷銆傚洜鐗╃悊鍜岀敓鐞嗕綔鐢紝鏈轰綋鑳藉閫夋嫨鎬у湴鍦ㄨ倽銆佽劸銆佽偤銆佹穻宸寸瓑閮ㄤ綅鑱氶泦涓嶅悓澶у皬鐨勮浇鑽剛璐ㄤ綋锛屼粠鑰屼娇鍏堕噴鏀捐嵂鐗╁彂鎸ヨ嵂鏁堛€侟sup>[7]姝ゅ锛岃繕鍙互閫氳繃妫€娴婞/span>Zeta鐢典綅瀵硅剛璐ㄤ綋绋冲畾鎬ц繘琛岃瘎浠凤紝Zeta鐢典綅瓒婇珮锛屼綋绯绘洿鍔犵ǔ瀹氥€侟/span>

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鍥近/span>2鈭堕珮鏂矑寰勫垎甯冨浘	鍥近/span>3鈭迭/span>Nicomp澶氬嘲绮掑緞鍒嗗竷鍥近/span>

NICOMP3000绯诲垪鐢ㄤ簬鑴傝川浣撶矑寰勬娴嬫渚婞/span>

閲囩敤GMV(giant multilamellar vesicle)锛欬/span>Sugar-doped lipidfilm hydration锛堣剛鑶滄按鍖栧弽娉曪級鏂瑰紡鍒跺鑴傝川浣擄紝瀵硅繃婊 鎸ゅ嚭宸ヨ壓鍓嶅悗鏍锋湰鑴傝川浣撶敤Nicomp 3000璁惧杩涜绮掑害妫€ 娴嬶紝娴嬭瘯缁撴灉濡傝〃1鎵€绀恒€侟/span>

Before Extrusion	After Extrusion through 0.4渭m Filter (3 times)
After Extrusion through 0.2渭m Filter (3 times)	After Extrusion through 0.1渭m Filter (3 times)

琛? GMV娉曞埗澶囪剛璐ㄤ綋杩囨护鍓嶅悗绮掑緞鍒嗗竷鍥撅紙Gaussian 鍒嗗竷锛堻/span>

鐢辫〃1鍙煡锛屾病鏈夎繃婊ゆ尋鍑哄墠Gaussian鍒嗗竷涓嬪钩鍧囦綋绉緞涓?237nm锛涚粡杩?.4渭m銆?.2渭m銆?.1渭m杩囨护鍣ㄨ繃婊ゆ尋鍑?娆″悗锛屽钩鍧囦綋绉緞涓?19nm銆?61nm銆?01nm锛涘钩鍧囩矑寰勬槑鏄鹃檷浣庛€傚叾Nicomp 鍒嗗竷濡傝〃2鎵€绀恒€侟/span>閫氳繃Nicomp鍒嗗竷鍙湡瀹炲弽鏄犺剛璐ㄤ綋绮掑緞鍒嗗竷鎯呭喌锛岀敱琛?涓彲鐭ワ紝鏈尋鍑鸿剛璐ㄤ綋浣撶Н绮掑緞Nicomp鍒嗗竷鏈変笁涓嘲锛涚粡杩?.4渭m杩囨护鍣ㄦ尋鍑哄悗涓変釜宄扮殑绮掑緞鍧囧噺灏忥紝缁忚繃0.2渭m杩囨护鍣ㄨ繃婊や箣鍚庡彉涓哄崟宄帮紝缁忚繃0.1渭m杩囨护鍣ㄨ繃婊や箣鍚庤幏寰楀垎甯冩洿鍔犵獎鐨勫崟宄般€侟/span>

Before Extrusion	After Extrusion through 0.4渭m Filter (3 times)
After Extrusion through 0.2渭m Filter (3 times)	After Extrusion through 0.1渭m Filter (3 times)

琛? GMV娉曞埗澶囪剛璐ㄤ綋杩囨护鍓嶅悗绮掑緞鍒嗗竷鍥撅紙Nicomp 鍒嗗竷锛堻/span>

瀵规瘮Gaussian鍙奛icomp鍒嗗竷缁撴灉鍙煡锛欸aussian鍒嗗竷鍙暣浣撳弽搴旇剛璐ㄤ綋绮掑緞鍒嗗竷鎯呭喌锛涜€孨icomp鍒嗗竷鏇寸湡瀹炲弽鏄犺剛璐ㄤ綋绮掑緞鍒嗗竷銆傞€氳繃Nicomp鏁版嵁鐨勫垎鏋愬彲浠ユ洿濂界殑甯姪鑴傝川浣撳埗澶囧伐鑹虹殑浼樺寲锛岄€夋嫨鍚堥€傜殑澶勭悊鏂瑰紡寰楀埌鎯宠鐨勭矑寰勮寖鍥存牱鏈€侟/span>

灏剧澶ч绮掑拰灏忕矑瀛愮殑妫€娴婞/span>

鐢ㄤ綔杞借嵂鍔熻兘鐨勮剛璐ㄤ綋骞冲潎绮掑緞涓€鑸负浜氬井绫崇骇鍒垨绾崇背绾у埆锛屼絾浠嶅瓨鍦ㄥ井绫崇骇鍒殑鑴傝川浣撶矑瀛愶紝灏剧澶ч绮掔殑瀛樺湪寰€寰€浼氬惛闄勫皬棰楃矑锛屽奖鍝嶈剛璐ㄤ綋鐨勭ǔ瀹氭€э紝鍒嗘瀽灏剧澶х矑瀛愭祿搴﹀拰鏁伴噺鍙互璇勪环褰撳墠閰嶆柟鍜屽伐鑹虹殑鎯呭喌骞跺仛鍑虹浉搴斾紭鍖栵紝渚嬪鐢ㄤ綔浣愬墏鐨勮剛璐ㄤ綋涓€鑸娴婞/span>0.8渭m~10渭m涔嬮棿鐨勫ぇ棰楃矑鍒嗗竷锛屼互纭繚宸ヨ壓鐨勭ǔ瀹氥€備负纭繚绾崇背鑽墿鐨勬湁鏁堟€э紝杩橀渶鎺у埗灏忕矑瀛愮殑娴撳害锛岃繃灏忕殑鑴傝川浣撶矑瀛愬鏄撹鑲捐剰娓呴櫎鍒板翱娑叉帓鍑猴紝鏃犳硶璧峰埌娌荤枟浣滅敤銆侟sup>[8]

AccuSizer棰楃矑璁℃暟鍣ㄧ郴鍒桙/span> AccuSizer绯诲垪鍦ㄦ娴嬫恫浣撲腑棰楃矑鏁伴噺鐨勫悓鏃剁簿纭娴嬮绮掔殑绮掑害鍙婄矑搴﹀垎甯冿紝閫氳繃鎼厤涓嶅悓浼犳劅鍣ㄣ€佽繘鏍峰櫒锛岄€傞厤涓嶅悓鐨勬牱鏈殑娴嬭瘯闇€姹傦紝鑳藉揩閫熻€屽噯纭湴娴嬮噺棰楃矑绮掑緞浠ュ強棰楃矑鏁伴噺/娴撳害銆侟/span> l妫€娴嬭寖鍥翠负0.5渭m-400渭m锛堝彲灏嗕笅闄忺/span>鎷撳睍鑷颤/span>0.15渭m锛夈€侟/span> l0.01渭m鐨勮秴楂樺垎杈ㄧ巼锛孅/span>AccuSizer绯诲垪鍏锋湁1024涓暟鎹€氶亾锛岃兘鍙嶆槧澶嶆潅鏍峰搧鐨勭粏寰樊寮傦紝涓虹爺鍙戝強鍝佹帶淇濋┚鎶よ埅銆侟/span> l鐏垫晱搴﹂珮杈近/span>10PPT绾у埆锛屽嵆浣垮彧鏈夊井閲忕殑棰楃矑閫氳繃浼犳劅鍣紝涔熷彲浠ョ簿鍑嗘娴嬪嚭鏉ャ€侟/span>

AccuSizer绯诲垪鐢ㄤ簬鑴傝川浣撶矑寰勬娴嬫渚

閲囩敤GMV(giant multilamellar vesicle)锛欬/span>Sugar-doped lipid-film hydration锛堣剛鑶滄按鍖栧弽娉曪級鏂瑰紡鍒跺鑴傝川浣擄紝瀵硅繃婊ゆ尋鍑宸ヨ壓鍓嶅悗鏍锋湰鑴傝川浣撶敤AccuSizer A7000璁惧杩涜绮掑害妫€娴嬶紝娴嬭瘯缁撴灉濡傝〃3鎵€绀恒€侟/span>

After Centrifugation	After Extrusion through 10.0渭m Filter (1 time)
After Extrusion through 5.0渭m Filter (1 time)	After Extrusion through 3.0渭m Filter (1 time)

琛? GMV娉曞埗澶囪剛璐ㄤ綋杩囨护鎸ゅ嚭鍚庣矑寰勫垎甯冨浘

鐢辫〃3鍙煡锛屼笂闈㈣摑鑹茶氨鍥句负鏁伴噺绮掑緞鍒嗗竷缁撴灉锛屼笅闈㈢孩鑹茶氨鍥句负浣撶Н绮掑緞鍒嗗竷娴嬭瘯缁撴灉銆傚垎鍒鍒跺鐨勮剛璐ㄤ綋鏍峰搧鐢10渭m銆?/span>5渭m銆?/span>3渭m杩囨护鍣ㄨ繃婊わ紝缁忚繃10渭m銆?/span>5渭m銆?/span>3渭m杩囨护鍣ㄧ殑鏁伴噺绮掑緞鍒嗗竷姣旀湭杩囨护鍓嶆祿搴︽洿浣庯紝浣嗘暟閲忕矑寰勫垎甯宸紓涓嶅ぇ锛涜瀵熶綋绉矑寰勫垎甯冿紝鍙煡锛氱粡杩嘃/span>10渭m銆?/span>5渭m杩囨护鍣ㄨ繃婊ゅ悗锛屼綋绉崰姣斾腑澶т簬绛変簬10渭m棰楃矑鏄庢樉鍑忓皯锛涚粡杩3渭m杩囨护鍣ㄨ繃婊ゅ悗锛孅/span>10渭m棰楃矑浣撶Н鍗犳瘮杩涗竴姝ュ噺灏戯紝涓斾富宄板凡涓嶅湪10渭m澶勶紝灏剧澶ч绮掓槑鏄惧噺灏戙€

绋冲畾鎬у垎鏋愭娴婞/span>

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LUM绋冲畾鎬у垎鏋愪华 LumiFuge绋冲畾鎬у垎鏋愪华鍙互鐩存帴娴嬮噺鏁翠釜鏍峰搧鐨勫垎鏁ｄ綋鐨勭ǔ瀹氭€э紝妫€娴嬪拰鍖哄垎鍚勭涓嶇ǔ瀹氱幇璞★紝濡侟/span>涓婃诞銆?/span>绲嚌銆佽仛闆嗐€佽仛缁掽/span>銆佹矇闄岦/span>绛夛紝閫氳繃娴嬮噺缁撴灉鍙敤鏉ュ紑鍙戞柊鐨勯厤鏂瑰拰浼樺寲鐜版湁鐨勯厤鏂更/span>鍙婂伐鑹裹/span>銆侟/span> l蹇€熴€佺洿鎺ユ祴璇曠ǔ瀹氭€э紝鏃犻渶绋€閲婏紝娓╁害鑼冨洿瀹藉箍 l鍙悓鏃舵祴8涓牱鍝侊紝娴嬮噺鍙婅鲸鍒笉鍚岀殑涓嶇ǔ瀹氱幇璞″強涓嶇ǔ瀹氭€ф寚鏁?/span> l鍔犻€熺蹇冿紝鏈€楂樼瓑鏁圏/span>2300鍊嶉噸鍔涘姞閫熷害

杩囨护

绮楄剛璐ㄤ綋缁忛珮鍘嬪井灏勬祦绛夎澶囨暣绮掍箣鍚庯紝闇€缁忚繃瓒呮护鎵嶈兘寰楀埌鏈€缁堢殑鑴傝川浣撴垚鍝併€傝秴婊ゆ槸浠ュ帇鍔涗负鎺ㄥ姩鍔涚殑鑶滃垎绂绘妧鏈箣涓€锛屼紭鐐规槸娌℃湁鐩歌浆绉伙紝鏃犻渶娣诲姞浠讳綍寮虹儓鍖栧鐗╄川锛屽彲浠ュ湪浣庢俯涓嬫搷浣滐紝杩囨护閫熺巼杈冨揩锛屼究浜庡仛鏃犺弻澶勭悊绛夈€傝秴婊ゆ妧鏈殑鍏抽敭鏄护鑶滐紝婊よ啘鏈夊悇绉嶄笉鍚岀殑绫诲瀷鍜岃鏍硷紝缁煎悎鑰冮噺鐗╃悊鎷︽埅锛屽惛闄勬嫤鎴瓑鏁堟灉锛岄€夋嫨閫傞厤鐨勬护鑶滄潗璐ㄧ敤浜庤繃婊ゃ€侟/span>

Entegris婊よ姱 Entegris-Anow鏄竴瀹堕珮鍒嗗瓙寰瓟鑶滆繃婊や紒涓氾紝涓撲笟浠庝簨MCE銆?/span>Nylon銆?/span>PES銆?/span>PVDF銆?/span>PTFE绛夛紙鑶滃瓟寰勪负0.03渭m~10渭m锛夊井瀛旇啘鐨勭爺鍙戝強鐢熶骇锛屽叿鏈変簩鍗佸骞存湇鍔′笌鍖昏嵂瀹㈡埛缁忛獙锛屽苟涓哄叏鐞冪敓鐗╁埗鑽€佸尰鐤楀櫒姊般€侀鍝侀ギ鏂欍€佸疄楠屽鍒嗘瀽銆佸井鐢靛瓙鍙婂伐涓氱瓑棰嗗煙鐨勫鎴锋彁渚涜繃婊ゃ€佸垎绂诲拰鍑€鍖栬В鍐虫柟妗堛€侟/span> Entegris涓嶞/span>Anow鐨勭粨鍚堬紝寮 鍏?/span>Entegris璐ㄩ噺绠＄悊浣掽/span>绯伙紝姣忎竴鏀护鑺兘缁忚繃涓ユ牸妫€鏌ワ紝姝ゅ锛屾柊寤烘垚鐨凕/span>CTC楠孅/span>璇佷腑蹇冿紝涓哄叏鐞冨鎴锋彁渚涗笓涓氱殑楠岃瘉鏈嶅姟銆侟/span>

鍙傝€冭祫鏂欙細

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[2]鐜嬪畤棣? 纾烽吀閿扮熆鍖栫撼绫宠嵂鐗╁強鍏舵姂鐧屼綔鐢ㄧ爺绌禰D].娴欐睙鐞嗗伐澶у,2022.

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[4]鐜嬪瘜鍠?閭撳畯鍥?鐜嬫花.闈跺悜鑴傝川浣撶殑鑽悊瀛﹁瘎浠穂J].鐜颁唬鍖昏嵂鍗敓,2023,39(01):137-140.

[5]鑴傝川浣撳叧閿伐鑹轰箣鎸ゅ嚭鍜岃秴婊｜/span>

[6]闄堢惣鐜?鍒樼孩鑺?鍒樹附,鐜嬪己.楂樺帇寰皠娴佹硶鍒跺鐧借棞鑺﹂唶绾崇背鑴傝川浣揫J].鏍稿啘瀛︽姤,2015,29(05):916-924.

[7]鐜嬪瘜鍠?閭撳畯鍥?鐜嬫花.闈跺悜鑴傝川浣撶殑鑽悊瀛﹁瘎浠穂J].鐜颁唬鍖昏嵂鍗敓,2023,39(01):137-140.

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