HM超高分子量MALDI质谱检测系�?参数-价格-中国粉体罐�/title>

<p><span>*</span>联系亹�/p> <input name="CName" type="text" placeholder="请输入您的姓�?/> </div> <div class="fxp_inp"> <p><span>*</span>单位名称</p> <input type="text" name="GuestType" placeholder="请输入您的单位名�?/> </div> <div class="fxp_inp"> <p><span>*</span>电子邮箱</p> <input type="email" name="Email" emailneed="1" placeholder="请输入您的电子邮�?/> </div> <div class="fxp_sj"> <p><span>*</span>手机叶�/p> <input type="text" name="Phone" placeholder="请输入您的手机号"/> </div> </form> </div> <div class="fxp_sub" onclick="return submitMsgFormByID('PopMsgFrom');" >提交</div> <div class="fxp_xieyi">点击提交代表您同� <a href="//www.znpla.com/service/registrationagreement.html" target="_blank">《用户服务协议《�/a>叉�a href="//www.znpla.com/about/privacy.php" target="_blank">《隐私协议《�/a></div> </div> </div> </div>  <div class="dhxj"> <div class="dhxjbox"> <img src="image24/close.png"/ class="dhxj_gb" onClick="close_telpopwin();"> <div class="dhxjbox_top"> <div class="dhxjbox_top_left"> <div id="nowvtel"></div> <p>虚拟号将� <span id="exptime">180</span> 秒后失效</p> </div> <div class="dhxjbox_top_rig"> <div id="telewm"></div> <p>使用微信扫码拨号</p> </div> </div> <div class="dhxjbox_bot"> 为了保证隐私安全，平台已启用虚拟电话，请放心拨打(暂不支持短信) </div> </div> <div class="dhxjbox2"> <span class="dhxj_gb2">×</span> <div class="dhxjbox2_tit">是否已沟通完戏�/div> <div class="dhxjbox2_tit2">您还可以选择留下联系电话，等待商家与您联糺�/div> <form id="TelPopMsgFrom" resultokclosewin="1" action="" method="post" onsubmit="return false;"><input name="FromPID" id="telafterfrompid" type="hidden" value="302024" /> <input type="hidden" name="CID" id="telaftercid" value="30887" /> <input type="hidden" name="leavetype" value="1" /> <div class="dhxjbox2_form"> <div class="dhxjbox2_form_inp"> <p>需求描�?/p> <input type="text" name="Content" placeholder="请输入您的需求描�?/> </div> <div class="dhxjbox2_form_inp"> <p>单位名称</p> <input type="text" name="GuestType" placeholder="请输入您所在单�?/> </div> <div class="dhxjbox2_form_inp"> <p>联系亹�/p> <input type="text" name="CName" placeholder="请输入您的联系人姓名"/> </div> <div class="dhxjbox2_form_inp"> <p>联系电话</p> <input type="text" name="Phone" placeholder="请输入您的联系电�?/> </div> <div class="dhxjbox2_form_inp"> <p>Email</p> <input type="email" name="Email" placeholder="请输入您的邮�?/> </div> </div> <div class="dhxjbox2_but"> <div>已与商家取得联系</div> <a href="javascript:void(0);" onclick="return submitMsgFormByID('TelPopMsgFrom');" >同意发送给商家</a> </div> </form> </div> </div> <script> var _cpjj = ""; var _cxd = ""; var _xgfa = ""; var _xgzl = ""; var _yhpl = ""; var _gsdt = ""; var _wsj = ""; $(function(){ // 留言询价显示 $(".js_lyxj").click(function(){ showliuyan(this, 0); }); $(".fxp_gb span").click(function(){ $(".fxp").css("display","none"); }); $(".dhxj_gb2").click(function(){ $(".dhxj").css("display","none"); $(".dhxjbox").css("display","block"); $(".dhxjbox2").css("display","none"); }); $(".dhxjbox2_but div").click(function(){ $(".dhxj").css("display","none"); $(".dhxjbox").css("display","block"); $(".dhxjbox2").css("display","none"); }); // 切换 $(".fixdbox_main_left a").click(function(){ $(".fixdbox_main_left a").css({"color":"#4F5862","border-bottom-color":"transparent"}); $(this).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }); $('.js_cpjj').click(function(){$('html,body').animate({scrollTop:$('.cpjj').offset().top-60}, 800);}); $('.js_cxd').click(function(){$('html,body').animate({scrollTop:$('.cxd').offset().top-60}, 800);}); $('.js_xgfa').click(function(){$('html,body').animate({scrollTop:$('.xgfa').offset().top-60}, 800);}); $('.js_xgzl').click(function(){$('html,body').animate({scrollTop:$('.xgzl').offset().top-60}, 800);}); $('.js_yhpl').click(function(){$('html,body').animate({scrollTop:$('.yhpl').offset().top-60}, 800);}); $('.js_gsdt').click(function(){$('html,body').animate({scrollTop:$('.gsdt').offset().top-60}, 800);}); $('.js_wsj').click(function(){$('html,body').animate({scrollTop:$('.wsj').offset().top-60}, 800);}); _cpjj = $(".cpjj").offset().top-60; _cxd = $(".cxd").offset().top-60; _xgfa = $(".xgfa").offset().top-60; _xgzl = $(".xgzl").offset().top-60; _yhpl = $(".yhpl").offset().top-60; _gsdt = $(".gsdt").offset().top-60; _wsj = $(".wsj").offset().top-60; }); $(window).resize(function(){ _cpjj = $(".cpjj").offset().top-60; _cxd = $(".cxd").offset().top-60; _xgfa = $(".xgfa").offset().top-60; _xgzl = $(".xgzl").offset().top-60; _yhpl = $(".yhpl").offset().top-60; _gsdt = $(".gsdt").offset().top-60; _wsj = $(".wsj").offset().top-60; }); $(document).scroll(function(){ if($(this).scrollTop() >= _cpjj){ $(".fixdbox").css({"display":"block"}); }else{ $(".fixdbox").css({"display":"none"}); } $(".fixdbox_main_left div").css({"color":"#4F5862","border-bottom-color":"transparent"}); if($(this).scrollTop()>=_wsj){ $(".fixdbox_main_left div").eq(6).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }else if($(this).scrollTop()>=_gsdt){ $(".fixdbox_main_left div").eq(5).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }else if($(this).scrollTop()>=_yhpl){ $(".fixdbox_main_left div").eq(4).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }else if($(this).scrollTop()>=_xgzl){ $(".fixdbox_main_left div").eq(3).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }else if($(this).scrollTop()>=_xgfa){ $(".fixdbox_main_left div").eq(2).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }else if($(this).scrollTop()>=_cxd){ $(".fixdbox_main_left div").eq(1).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }else if($(this).scrollTop()>=_cpjj){ $(".fixdbox_main_left div").eq(0).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); } }); function showliuyan(me, showtype){ if(showtype==0){ //$("#Content").val($("#Content").attr('placeholder')); Content= document.getElementById('PopMsgFrom').Content.getAttribute('placeholder'); document.getElementById('PopMsgFrom').Content.value=Content; } if(showtype==1){ // $("#Content").val($(me).text()); alert($(me).text()); document.getElementById('PopMsgFrom').Content.value=$(me).text(); } $(".fxp").css("display","flex"); } function close_popwin(){ $(".fxp").css("display","none"); // 关闭虚拟电话后的留言� $(".dhxj").css("display","none"); $(".dhxjbox").css("display", "none"); $(".dhxjbox2").css("display", "none"); return false; } </script>  <div class="cpjs"> <div class="cpjs_tab"> <div class="js_cpjj" style="border-bottom: 3px solid #1479d7; color: #1479d7;">产品介绍</div> <div class="js_cxd">创新炸�/div> <div class="js_xgfa">相关方案</div> <div class="js_xgzl">相关资料</div> <div class="js_yhpl">用户评论</div> <div class="js_gsdt">公司动�?/div> <div class="js_wsj">问商宵�/div> </div> <script> $(function(){ // 切换 $(".cpjs_tab a").click(function(){ $(".cpjs_tab a").css({"color":"#4F5862","border-bottom-color":"transparent"}); $(this).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }); }); </script>  <div class="cpjj"> <p><span>HM4 </span><span>� </span><span>Pearl </span><span>为第四代“超”高分子� </span><span>MALDI </span><span>质谱检测系统，基于独特的转换打拿极技术，扩展 </span><span>MALDI </span><span>质谱检测质量上限到 </span><span>2</span><span>50 </span><span>� </span><span>Da </span><span>以上，实� </span><span>nM </span><span>浓度的超痕量、大分子抗体药物和蛋白质复合物的高灵敏度分析。在诸如蛋白质复合物测定、蛋白质相互作用、抗原抗体相互作用、蛋白质聚集分析、高分子� </span><span>MALDI </span><span>质谱成像、临床转化医学、生物制药等领域的应用卓有成效、�/span></p><p><span>传统� </span><span>ESI </span><span>对于生物大分子的检测，除需要耗时的色谱分离外，对获得的多电荷谱图进行去卷积也使数据分析变得异常复杂，� </span><span>HM4 </span><span>� </span><span>Pearl </span><span>第四代“超”高分子� </span><span>MALDI </span><span>检测系统，可以对超高分子量蛋白复合物或聚合物的检测提供简便直观、超灵敏的单电荷数据、�/span></p><p><span>HM4 </span><span>� </span><span>Pearl </span><span>兼容主流 </span><span>MALDI </span><span>质谱厂商� </span><span>TOF </span><span>� </span><span>TOF/TOF </span><span>质谱仪，只需稍加优化改造，</span><span>HM4 </span><span>� </span><span>Pearl </span><span>与原有检测器兼容，轻松实现两者间的快速切换，互不干扰。操作者能直接观察和比较两种检测器对大分子分析显著的性能差异。典型应用包括：蛋白质复合物测定、蛋白质相互作用、抗原抗体相互作用、蛋白质聚集分析、高分子� </span><span>MALDI </span><span>质谱成像、�/span></p><p><span>目前国内没有生产该类离子源，因此无法满足课题的实际需求。所以，该设备采购国际知名厂家提供的仪器，无论是从厂商的技术实力、制造经验（超过十年）和制造精度，还是从设备的处理速率和通量上来看，</span><span>CovalX </span><span>皃�/span><span>HM4 </span><span>� </span><span>Pearl </span><span>“超”高分子� </span><span>MALDI </span><span>检测系统都是国�?***，国内尚未生产的尖端设备。检测系统的核心组件为主真空管部件，主要包括 </span><span>HM </span><span>新型检测器、信号保护、高真空腔、内置的高真空马达和必要的支架及电缆线。主真空管的设计包含一系列�?*技术，包括化学镀镍防微泄露，充分保障主真空管�?*真空水平的检测性能（详询国�?*叶�/span><span>WO 2009086642</span><span>）、�/span></p><p><span><strong><span>创新点介绌�/span></strong></span><span><strong><span>９�/span></strong></span></p><p><span>传统� </span><span>MALDI-TOF </span><span>多采� </span><span>MCP</span><span>（集成微通道板）作为检测器，越大的生物大分子飞行速度越慢，撞击到微通道板后，产生的次级电子信号较弱，会导致过低的响应灵敏度；另外由于微通道直径长度会影响离子进行电子倍增反射的时间响应，存在“死时间”现象，即首先到达的离子如果抢占了微通道，则后续到达同一通道的离子无法进行电子培增反射，即出现所谓的检测器饱和问题。因此传统的 </span><span>MALDI-TOF </span><span>检测器只能检测到质量上限�?/span><span>100KDa </span><span>的生物大分子，无法获得更大质量数的优质数据，这将让您无法获得感兴趣的重要样品信息</span><span>! </span></p><p><span>� </span><span>HM4 </span><span>� </span><span>Pearl </span><span>型检测器的技术革新在于：带电的生物大分子先与**级打拿极撞击产生更重的次级离子，后者在</span><span>20KV </span><span>加速电场的作用下，以较高的动能撞击第二级打拿极，产生的电子经过电子倍增放大而获得更高的灵敏度。这种独特的基于两级打拿极转换和新型的电子倍增器技术，不存在次级离子和电子传输的信号饱和的现象，因此可以扩� </span><span>MALDI </span><span>质谱检测质量上限提升到</span><span>2</span><span>百万 </span><span>Da </span><span>以上，轻松实� </span><span>nM </span><span>浓度的超痕量、大分子抗体药物和蛋白质复合物的高灵敏度分析、�/span></p><p><span>标准检测器咋�/span><span> HM4 </span><span>检测器之间�?/span><span> HM </span><span>控制器选择切换，同等实验条件下的结果对比：</span><span>HM4 </span><span>既保证了大量的高分子量大分子（如</span><span> Insulin� BSA </span><span>咋�/span><span> IgG clusters) </span><span>的分析灵敏度，又避免了高丰离子信号的饱和，真实的反映了蛋白质复合物的相对丰度和含量、�/span></p><p><span></span></p><p><span></span></p><p><span><strong><span>其创新点总结如下９�/span></strong></span></p><p><span>a.<strong><span>灵敏</span></strong><span>：实�?*灵敏度的完整蛋白复合物的分析、�/span></p><p><span>b.<strong><span>超高分子野�/span></strong><span>：无可比拟的动态响应范围，检测分子量范围� </span><span>250</span><span> 丆�/span><span>Da、�/span></p><p><span>c.<span>阴、阳双离子标准检测、�/span></p><p><span>d.<strong><span>简匕�/span></strong><span>：方案优化的交联或样品处理试剂，简� </span><span>MALDI </span><span>样品的制备、�/span></p><p><span>e.<strong><span>直观</span></strong><span>：“复合物示踪”分析软件，直观易懂、�/span></p><p><span><strong></strong><span><strong></strong><span>f<span>.</span></span><strong><span>兼容</span></strong><span>：与</span><span> SCIEX</span><span>�?/span><span>Shimadzu</span><span>�?/span><span>Bruker </span><span>等主流品牌的主打</span><span> MALDI-TOF </span><span>咋�/span><span> TOF/TOF </span><span>品牌兼容</span>、�/p><p><span><strong><span>设备主要用途：</span></strong></span></p><p><span>HM4 </span><span>� </span><span>Pearl </span><span>第四代“超”高分子� </span><span>MALDI </span><span>质谱检测系统基于独特的转换打拿极技术，扩展 </span><span>MALDI </span><span>质谱检测质量上限到 </span><span>250 </span><span>� </span><span>Da </span><span>以上，实� </span><span>nM </span><span>浓度的超痕量、大分子抗体药物和蛋白质复合物的高灵敏度分析。在诸如蛋白质复合物测定、蛋白质相互作用、抗原抗体相互作用、蛋白质聚集分析、高分子� </span><span>MALDI </span><span>谱成像、临床转化医学、生物制药，等领域的应用卓有成效。带电的生物大分子先�?*级打拿极撞击产生更重的次级离子，后者在</span><span>20KV </span><span>加速电场的作用下，以较高的动能撞击第二级打拿极，产生的电子经过电子倍增放大而获得更高的灵敏度。这种独特的基于两级打拿极转换和新型的电子倍增器技术，不存在次级离子和电子传输的信号饱和的现象，因此可以扩� </span><span>MALDI </span><span>质谱检测质量上限提升到 </span><span>2</span><span>50</span><span>Da </span><span>以上，轻松实� </span><span>nM </span><span>浓度的超痕量、大分子抗体药物和蛋白质复合物的高灵敏度分析、�/span></p><p><span><strong><span>仪器或技术设备名称：</span></strong></span></p><p><span>“超”高分子� <span>MALDI </span>检测器＇�span>HM4</span> � <span>Pearl</span>（�/span></p><p><span>生产商为 <span>CovalX</span>（瑞士苏黎世）；中国**总代理为华质泰科生物技术（北京）有限公司、�/span></p> </div>  <div class="cxd"> <div class="cxd_tit"><span></span>创新炸�/div> <p style=" color: #333; font-size: 14px; margin: 10px 0 0; line-height: 26px;"> 暂无数据� </p> </div>  <div class="xgfa"> <div class="xgfa_tit"> <div> <span></span>相关方案 </div> </div> <div class="xgfa_box" style="display: block;"><div style="padding:10px;">暂无相关方案、�/div> </div> </div> <script> $(function(){ // 切换 $(".xgfa_tit_ul li").hover(function(){ $(".xgfa_tit_ul li").css({"color":"#4F5862","border-bottom-color":"transparent"}); $(this).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); var _index = $(this).index(); $(".xgfa_box").css("display","none"); $(".xgfa_box").eq(_index).css("display","block"); }); }); </script>  <div class="xgzl"> <div class="cxd_tit"><span></span>相关资料</div> <div class="xgzl_box"><div style="padding:10px;">暂无数据、�/div> </div> </div>  <div class="yhpl"> <div class="cxd_tit"><span></span>用户评论</div> <form id="FormComments" action="" method="post" onsubmit="return false"> <input name="SaveProComments" id="SaveProComments" type="hidden" value="yes" /> <input name="ProductID" id="ProductID" type="hidden" value="302024" /> <input name="ProQuality" id="ProQuality" type="hidden" value="10" /> <input name="ProService" id="ProService" type="hidden" value="10" /> <input name="ProUsability" id="ProUsability" type="hidden" value="10" /> <input name="ProCostperformance" id="ProCostperformance" type="hidden" value="10" /> <div class="yhpl_pf"> <div> <p>产品质量</p> <div><span id="Quality" class="stars star10"></span><span id="Quality_Val" class="ScoreVal" curScore="10">10刅�/span></div> </div> <div> <p>售后服务</p> <div><span id="Service" class="stars star10"></span><span id="Service_Val" class="ScoreVal" curScore="10">10刅�/span></div> </div> <div> <p>易用�?/p> <div><span id="Usability" class="stars star10"></span><span id="Usability_Val" class="ScoreVal" curScore="10">10刅�/span></div> </div> <div> <p>性价毓�/p> <div><span id="Costperformance" class="stars star10"></span><span id="Costperformance_Val" class="ScoreVal" curScore="10">10刅�/span></div> </div> </div> <div class="yhpl_pftit">评论内容</div> <textarea name="Comments" id="ProComments" onfocus="checklogin();" placeholder="分享产品使用经验/采购评价（不超过500字）">