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Cerebus多通道神经信号记录系统
产品简今span>:
Blackrock Microsystems Inc是一家致力于将直接探测脑神经信号,在线分析和记录神经信号以及神经刺激技术平台商业化的高科技制造商、span>Blackrock总部设在美国犹他州盐湖城、span>Blackrock为脑和神经系统的基础研究,脑机接口和神经修复研究提供了有效的工具。目前公司已在将脑神经信号转化为行为,植入无线阵列电极等领域取得了突破性的进展、/span>
Cerebus系统是记录和分析大脑和周边神经系统信号的数据采集硬件和软件系统,包括微电极阵列,连接器,神经信号采集系统和应用软件。是用于动物神经生理学实验的多通道数据采集系统,功能强大且操作简便。该系统是多辽span>1024个电极的先进的多通道系统,可以记录和分析动物大脑和周围神经电活动。该系统配置可以记录在麻醉或清醒状态下的动物(鸟类,小鼠,大鼠,猫,灵长类动物)体内电信号。而且还支持体外培养细胞的微电?span>plates和脑切片chambers的记录、/span>
技术原理:可以对每个通道的多个神经元在线进行的手动模式分类和自动模式分类,提供Hoops (Manual)、Manual PCA、K-means PCA、DBSCAN PCA等多种分类算法、/span>
可以对每个通道的任意个神经元离线进行手动模式分类和自动模式分类,提侚span>Hoops (Manual)?span>Manual PCA?span>K-means PCA?span>DBSCAN PCA等多种分类算法、/span>
CerePlex Direct通过各种接口'span>CerePort? MultiPort?,ICS-96,Rodent等)可以和不同通道数的各种电极(犹他电极,微丝电极+span>Silicon probes+span>Microelectrode arrays+span>Individual,metal microelectrodes)相连接、/span>
可以使用各种电极植入装置,如9span>Inserter,Electrode Drives等、/span>
应用领域9/span>
脑科学研穵/span>
神经影像、神经信号处琅/span>
脑机接口
癫痫及相关疾病研穵/span>
生物工程&生物?/span>
神经科学
应用案例(点击查看)
中国科学院上海神经研究所姚海珊教授在〉span>Nature》上发表一篇研究性文章。该研究使用了植入式微电极阵列和Cerebus在体多通道神经信号采集系统,同时结合了光遗传技术,采集小鼠视觉皮层的神经元放电信息。研究结果表明表明,光遗传抑制小白蛋白(PV)削弱了自然刺激的神经辨别,而生长激素抑制素'span>SOM)则不能起到相同效果。从而揭示了自然刺激过程中,光遗传抑制小白蛋白的中间神经元在可靠的视觉皮层重现模式中起到了重要作用、/span>
文章信息9/span>
Control of response reliability by parvalbumin-expressing interneurons in visual cortex.Yingjie Zhu WenhuiQiao Kefei Liu HuiyuanZhong&Haishan Yao. Nature Communications 6 Article number: 6802
Cerebus多通道神经信号记录系统规格参数9/span> 设计紧凑,体积小?/span> 无噪声干扰的长距离光纤线缆连?/span> 8 16 32 64 96 128 256 512咋span>1024通道配置 高分辨率信号记录(30 kHz / 60 kHzat 16 bits up to 120 kHz ) 共模抑制毓span> > 120dB 输入参考噪?span>< 1.0 Vrms 输入频率范围0.01 Hz - 10 k Hz 与各种低、高阻抗电极相兼宸/span> 电极阻抗测试功能(在体状态或离体状态) 灵活皃span> I/O设置,用于与行为、刺激和视频系统同?/span> 并行多台PC控制与操佛/span> |
文献列表
Closed-loop stimulation of temporal cortex rescues functional networks and improves memory
February 6 2018
Closed-loop stimulation of temporal cortex rescues functional networks and improves memory Youssef Ezzyat Paul A. Wanda Deborah F. Levy Allison Kadel Ada Aka Isaac Pedisich Michael R. Sperling Ashwini D. Sharan Bradley C. Lega Alexis Burks Robert E. Gross Cory S. Inman Barbara C. Jobst Mark A. Gorenstein Kathryn A....
Restoration of motor control and proprioceptive and cutaneous sensation in humans with prior upper-limb amputation via multiple Utah Slanted Electrode Arrays (USEAs) implanted in residual peripheral arm nerves
November 25 2017
Restoration of motor control and proprioceptive and cutaneous sensation in humans with prior upper-limb amputation via multiple Utah Slanted Electrode Arrays (USEAs) implanted in residual peripheral arm nerves Suzanne Wendelken David M. Page Tyler Davis Heather A. C. Wark David T. Kluger Christopher Duncan David J. Warren Douglas T. Hutchinson...
Direct Brain Stimulation Modulates Encoding States and Memory Performance in Humans
April 20 2017
Direct Brain Stimulation Modulates Encoding States and Memory Performance in Humans Youssef Ezzyat James E. Kragel John F. Burke Deborah F. Levy Anastasia Lyalenko Paul Wanda Logan O’Sullivan Katherine B. Hurley Stanislav Busygin Isaac Pedisich Michael R. Sperling Gregory A. Worrell Michal T. Kucewicz Kathryn A. Davis Timothy H. Lucas?..
Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration
March 28 2017
Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration Dr A Bolu Ajiboye PhD? Francis R Willett BS? Daniel R Young BS William D Memberg MS Brian A Murphy PhD Jonathan P Miller MD Benjamin L Walter MD Jennifer A Sweet?..
Intracortical microstimulation of human somatosensory cortex
October 19 2016
Intracortical microstimulation of human somatosensory cortex Sharlene N. Flesher Jennifer L. Collinger Stephen T. Foldes Jeffrey M. Weiss John E. Downey Elizabeth C. Tyler-Kabara Sliman J. Bensmaia Andrew B. Schwartz Michael L. Boninger and Robert A. Gaunt* Science Translational Medicine 2016 Published Online ? The Author(s). 2016 Published: 19 October...
国内部分用户名单
中国科学院神经科学研究所
中国科学院心理研究所
中国科学技术大?/span>
清华大学
北京大学
上海交通大?/span>
复旦大学
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