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$(this).css({"color":"#1479d7","border-bottom-color":"#1479d7"}); }); }); </script>  <div class="cpjj"> <p><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">为什么药片剂压成后，硬度不够，表面有麻孔，用手指轻轻加压即碎裂？</span><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">原因分析及解决方法：</span><br style="margin: 0px; padding: 0px; cursor: unset; font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);"/><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">①药物粉碎细度不够、纤维性或富有弹性药物或油类成分含量较多而混合不均匀。可将药物粉碎过100目筛、选用黏性较强的黏合剂、适当增加压片机的压力、增加油类药物吸收剂充分混匀等方法加以克服、�/span><br style="margin: 0px; padding: 0px; cursor: unset; font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);"/><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">②黏合剂或润湿剂用量不足或选择不当，使颗粒质地疏松或颗粒粗细分布不匀，粗粒与细粒分层。可选用适当黏合剂或增加用量、改进制粒工艺、多搅拌软材、混均颗粒等方法加以克服、�/span><br style="margin: 0px; padding: 0px; cursor: unset; font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);"/><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">③颗粒含水量太少，过分干燥的颗粒具有较大的弹性、含有结晶水的药物在颗粒干燥过程中失去较多的结晶水，使颗粒松脆，容易松裂片。故在制粒时，按不同品种应控制颗粒的含水量。如制成的颗粒太干时，可喷入适量稀乙醇�?0%�?0%），混匀后压片、�/span><br style="margin: 0px; padding: 0px; cursor: unset; font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);"/><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">④药物本身的性质。密度大压出的片剂虽有一定的硬度，但经不起碰撞和震摇。如次硝酸铋片、苏打片等往往易产生松片现象；密度小，流动性差，可压性差，重新制粒、�/span><br style="margin: 0px; padding: 0px; cursor: unset; font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);"/><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">⑤颗粒的流动性差，填入模孔的颗粒不均匀、�/span><br style="margin: 0px; padding: 0px; cursor: unset; font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);"/><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">⑥有较大块或颗粒、碎片堵塞刮粒器及下料口，影响填充量、�/span><br style="margin: 0px; padding: 0px; cursor: unset; font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);"/><span style="font-family: Arial; font-size: 13.3333px; white-space: pre-wrap; caret-color: rgb(30, 111, 255); background-color: rgb(255, 255, 255);">⑦压片机械的因素。压力过小，多冲压片机冲头长短不齐，车速过快或加料斗中颗粒时多时少。可调节压力、检查冲模是否配套完整、调整车速、勤加颗粒使料斗内保持一定的存量等方法克服、�/span><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112126_479368_procont.jpg" style="" title="112126_479368_procont.jpg"/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112126_627590_procont.jpg" style="" title="112126_627590_procont.jpg"/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112126_681819_procont.jpg" style="" title="112126_681819_procont.jpg"/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112127_006919_procont.jpg" style="" title="112127_006919_procont.jpg"/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112127_022777_procont.jpg" style="" title="112127_022777_procont.jpg"/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112127_029288_procont.jpg" style="" title="112127_029288_procont.jpg"/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112127_233281_procont.jpg" style="" title="112127_233281_procont.jpg"/><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112248_984524_procont.jpg" title="112248_984524_procont.jpg"/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112249_027599_procont.jpg" style="" title="112249_027599_procont.jpg"/></p><p><br/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112249_348402_procont.jpg" style="" title="112249_348402_procont.jpg"/></p><p><img src="https://img1.cnpowder.com.cn/img/daily/2021/05/20/112249_399143_procont.jpg" style="" title="112249_399143_procont.jpg"/></p><p><br/></p><p><br/></p> </div>  <div class="cxd"> <div class="cxd_tit"><span></span>创新炸�/div> <p style=" color: #333; font-size: 14px; margin: 10px 0 0; line-height: 26px;"> 原因分析及解决方法：<br /> ①药物粉碎细度不够、纤维性或富有弹性药物或油类成分含量较多而混合不均匀。可将药物粉碎过100目筛、选用黏性较强的黏合剂、适当增加压片机的压力、增加油类药物吸收剂充分混匀等方法加以克服、�br /> ②黏合剂或润湿剂用量不足或选择不当，使颗粒质地疏松或颗粒粗细分布不匀，粗粒与细粒分层。可选用适当黏合剂或增加用量、改进制粒工艺、多搅拌软材、混均颗粒等方法加以克服、�br /> ③颗粒含水量太少，过分干燥的颗粒具有较大的弹性、含有结晶水的药物在颗粒干燥过程中失去较多的结晶水，使颗粒松脆，容易松裂片。故在制粒时，按不同品种应控制颗粒的含水量。如制成的颗粒太干时，可喷入适量稀乙醇�?0%�?0%），混匀后压片、�br /> ④药物本身的性质。密度大压出的片剂虽有一定的硬度，但经不起碰撞和震摇。如次硝酸铋片、苏打片等往往易产生松片现象；密度小，流动性差，可压性差，重新制粒、�br /> ⑤颗粒的流动性差，填入模孔的颗粒不均匀、�br /> ⑥有较大块或颗粒、碎片堵塞刮粒器及下料口，影响填充量、�br /> ⑦压片机械的因素。压力过小，多冲压片机冲头长短不齐，车速过快或加料斗中颗粒时多时少。可调节压力、检查冲模是否配套完整、调整车速、勤加颗粒使料斗内保持一定的存量等方法克服� </p> </div>  <div class="xgfa"> <div class="xgfa_tit"> <div> <span></span>相关方案 </div> </div> <div class="xgfa_box" style="display: block;"><div class="xgfa_cont"><a href="//www.znpla.com/mitrcn/solution_201.html" target="_blank" class="xgfa_cont_img"><img src=""/></a> <div class="xgfa_cont_rig"><a href="//www.znpla.com/mitrcn/solution_201.html" target="_blank">球磨机对于磁性材料混合的优势</a> <p class="xgfa_cont_txt">有客户提问：目前我们课题组研究的是磁性材料，软磁和硬磁方面，物料必须一定程度上混合均匀，是用哪方面的设备呢?对于这个问题，根据我公司多年来的经验追溯，做磁性材料的集中�?种型号较为常用，一种是滚筒式罐</p><div class="xgfa_cont_time"> <p>2020-07-04</p></div></div></div> </div> </div> <script> $(function(){ // 切换 $(".xgfa_tit_ul li").hover(function(){ $(".xgfa_tit_ul li").css({"color":"#4F5862","border-bottom-color":"transparent"}); 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