浣跨敤鏁版嵁鍒嗘瀽鍜岀數瀛愭樉寰暅鍙戠幇鏉愭枡鐨勬柊鏂规硶宸茬粡鍙戠幇浜嗕竴绫绘柊鐨勬瀬纭悎閲慄/span>銆侟/span>杩欑鏉愭枡鍙兘鎵垮彈瀛愬脊鐨勪弗閲嶅啿鍑狐/span>锛孅/span>浠庤€屼负澹叺鎻愪緵鏇村ソ鐨勬垬鏂椾繚鎶｜/span>銆侟/span>鐞嗘捣澶у鐨勭爺绌朵汉鍛樺湪浠婂ぉ鍑虹幇鍦?/span>Nature Communications涓婄殑涓€绡囨枃绔燑/span>鈥淈/span>鐢ㄤ簬绛涢€夊涓诲厓绱犲拰楂樼喌鍚堥噾鐨勬潗鏂欎俊鎭鈥滭/span>涓弿杩颁簡杩欑鏂规硶鍜屽彂鐜?/span>銆侟/span>

鈥滄垜浠娇鐢ㄦ潗鏂欎俊鎭鈥斺€斿皢鏁版嵁绉戝鏂规硶搴旂敤浜庢潗鏂欓棶棰樷€斺€旀潵棰勬祴涓€绫诲叿鏈変紭寮傛満姊版€ц兘鐨勬潗鏂欙紝鈥濅富瑕佷綔鑰匤effrey M. Rickman璇达紝浠栨槸鐞嗘捣澶у鏉愭枡绉戝涓庡伐绋嬪拰鐗╃悊瀛︽暀鎺堛€侟/span>

鐮旂┒浜哄憳杩樹娇鐢ㄧ數瀛愭樉寰暅绛夊疄楠屽伐鍏饵/span>锛孅/span>娣卞叆浜嗚В瀵艰嚧楂樼喌鍚堥噾锛圚EAs锛堻/span>鐨勬潗鏂欑被涓瀵熷埌鐨勭幇璞＄殑鐗╃悊鏈哄埗銆侟/span>楂樼喌鍚堥噾鍚湁璁稿涓嶅悓鐨勫厓绱燑/span>锛孅/span>褰撳畠浠粍鍚堟椂锛孅/span>鍙兘瀵艰嚧绯荤粺鍏锋湁鏈夌泭涓旀湁鏃跺嚭涔庢剰鏂欑殑鐑拰鏈烘鎬ц兘銆侟/span>鍥犳锛孅/span>瀹冧滑鐩墠鏄縺鐑堢爺绌剁殑涓婚銆侟/span>

鈥滄垜浠涓烘垜浠紑鍙戠殑鎶€鏈皢鏈夊姪浜庤瘑鍒湁鍓嶆櫙鐨凥EA锛屸€漅ickman璇淬€傗€滀絾鏄紝鎴戜滑鍙戠幇鍚堥噾鐨勭‖搴﹀€艰秴杩囦簡鎴戜滑鏈€鍒濈殑棰勬湡銆傚畠浠殑纭害鍊兼瘮鍏朵粬鏇村吀鍨嬬殑楂樼喌鍚堥噾鍜屽叾浠栫浉瀵圭‖鐨勪簩鍏冨悎閲戦珮鍑虹害2鍊嶃€傗€滭/span>

鎵€鏈変竷浣嶄綔鑰呴兘鏉ヨ嚜鐞嗘捣澶у锛孅/span>鍖呮嫭閲屽厠鏇稽/span>; Helen M. Chan锛孅/span>鏂版辰瑗垮窞閿屾潗鏂欑瀛︿笌宸ョ▼鏁欐巿;缇庡浗閾濅笟鍩虹鏉愭枡绉戝涓庡伐绋嬫暀鎺圏/span>Martin P. Harmer; Joshua Smeltzer锛孅/span>鏉愭枡绉戝涓庡伐绋嬩笓涓氱殑鐮旂┒鐢烖/span>; Christopher Marvel锛孅/span>鏉愭枡绉戝涓庡伐绋嬪崥澹悗鐮旂┒鍛楛/span>; Ankit Roy锛孅/span>鏈烘宸ョ▼鍜屾満姊颁笓涓氱殑鐮旂┒鐢烖/span>; Ganesh Balasubramanian锛孅/span>鏈烘宸ョ▼鍜屽姏瀛﹀姪鐞嗘暀鎺圏/span>銆侟/span>

楂樼喌鍚堥噾鐨勫叴璧蜂笌鏁版嵁鍒嗘瀽

鏈€杩慄/span>锛孅/span>楂樼喌鎴栧涓诲厓绱犲悎閲戦鍩熷嚭鐜颁簡鎸囨暟澧為暱銆侟/span>杩欎簺绯荤粺浠ｈ〃浜嗗悎閲戝紑鍙戠殑鑼冨紡杞彉锛孅/span>鍥犱负涓€浜涚郴缁熻〃鐜板嚭鐩稿浜庝紶缁熷悎閲戠殑鏂扮粨鏋勫拰浼樺紓鐨勬満姊版€ц兘锛孅/span>浠ュ強澧炲己鐨勬姉姘у寲鎬у拰纾佹€?/span>銆侟/span>鐒惰€孅/span>锛孅/span>閴翠簬鍙兘瀛樺湪鐨勫悇绉嶅彲鑳藉厓绱犲拰缁勫悎锛孅/span>纭畾鏈夊墠鏅殑HEA宸茬粡鎻愬嚭浜嗕竴椤硅壈宸ㄧ殑鎸戞垬銆侟/span>

鐮旂┒浜哄憳宸茬粡瀵绘壘涓€绉嶆柟娉曟潵纭畾瀵艰嚧楂樺己搴?/span>锛孅/span>楂樼‖搴﹀悎閲戝拰鍏朵粬鎵€闇€鍝佽川鐨勫厓绱犵粍鍚堝拰鎴愬垎锛孅/span>杩欎簺鍝佽川鏄彲鑳戒骇鐢熺殑澶ч噺娼滃湪HSA鐨勭浉瀵硅緝灏忕殑瀛愰泦銆侟/span>

杩戝勾鏉?/span>锛孅/span>鏉愭枡淇℃伅瀛?/span>锛孅/span>鏁版嵁绉戝鍦ㄦ潗鏂欑瀛︿笌宸ョ▼涓殑搴旂敤锛孅/span>宸叉垚涓烘潗鏂欏彂鐜板拰璁捐鐨勬湁鍔涘伐鍏饵/span>銆侟/span>鐩稿杈冩柊鐨勯鍩熷凡缁忓鍚勭鏉愭枡绯荤粺鐨勬暟鎹В閲婁骇鐢熶簡閲嶅ぇ褰卞搷锛孅/span>鍖呮嫭鐢ㄤ簬鐑數鏉愭枡锛孅/span>閾佺數浣掽/span>锛孅/span>鐢垫睜闃虫瀬鍜岄槾鏋?/span>锛孅/span>鍌ㄦ阿鏉愭枡鍜岃仛鍚堢墿鐢典粙璐ㄧ殑鏉愭枡銆侟/span>

鈥滅壒鍒槸鍦ㄦ潗鏂欑瀛︿腑鍒涘缓澶у瀷鏁版嵁闆嗭紝姝ｅ湪璇ラ鍩熺殑鐮旂┒鏂瑰紡锛屾彁渚涜瘑鍒鏉傚叧绯荤殑鏈轰細锛屽苟鎻愬彇鑳藉瀹炵幇鏂板彂鐜板拰鍌寲鏉愭枡璁捐鐨勪俊鎭紝鈥漅ickman璇淬€傛暟鎹瀛︾殑宸ュ叿锛屽寘鎷鍙橀噺缁熻锛屾満鍣ㄥ涔狅紝闄嶇淮鍜屾暟鎹彲瑙嗗寲锛屽凡缁忓鑷翠簡缁撴瀯鈥斺€旀€ц川鈥斺€斿姞宸ュ叧绯荤殑璇嗗埆锛屾湁甯屾湜鍦ㄥ悎閲戠殑绛涢€変互鍙婂井瑙傜粨鏋勪笌鍔犲伐鍙傛暟鐨勭浉鍏虫€?/span>銆侟/span>

鐞嗘捣澶у鐨勭爺绌堕€氳繃璇佹槑杩欏宸ュ叿瀵逛簬浠庝紬澶氬彲鑳芥€т腑璇嗗埆鏈夊墠閫旂殑鏉愭枡闈炲父鏈夌敤锛孅/span>浠庤€屼负鏉愭枡淇℃伅瀛﹂鍩熷仛鍑轰簡璐＄尞銆傗€淈/span>杩欎簺宸ュ叿鍙互鍦ㄥ悇绉嶇幆澧冧腑浣跨敤锛孅/span>浠ョ缉灏忓ぇ鍨嬪疄楠屽弬鏁扮┖闂滁/span>锛孅/span>浠庤€屽姞閫熷鎵炬柊鏉愭枡锛屸€漅ickman璇滁/span>銆侟/span>

鐞嗘捣澶у鐨勭爺绌朵汉鍛樺皢涓ょ浜掕ˉ宸ュ叿缁撳悎璧锋潵锛孅/span>閲囩敤鐩戠潱瀛︿範绛栫暐锛孅/span>鏈夋晥绛涢€夐珮鐔靛悎閲慄/span>锛孅/span>骞剁‘瀹氭湁鍓嶉€旂殑HEAs锛氾紙1锛堻/span>鍏稿瀷鐩稿叧鍒嗘瀽锛?锛堻/span>鐢ㄥ吀鍨嬬浉鍏冲垎鏋愬惎鍙戠殑閫傚簲搴﹀嚱鏁扮殑閬椾紶绠楁硶銆侟/span>

浠栦滑浣跨敤瀛樺湪鏈烘鎬ц兘淇℃伅鐨勬暟鎹簱瀹炴柦姝ょ▼搴廃/span>锛孅/span>骞剁獊鍑烘樉绀哄叿鏈夐珮纭害鐨勬柊鍚堥噾銆侟/span>閫氳繃姣旇緝棰勬祴鐨勭‖搴︿笌鍦ㄥ疄楠屽涓娇鐢ㄧ數寮х啍鐐煎埗閫犵殑鍚堥噾锛孅/span>璇嗗埆鍏锋湁闈炲父楂樼殑娴嬮噺纭害鐨勫悎閲戞潵楠岃瘉璇ユ柟娉旤/span>銆侟/span>

鈥滆繖閲岄噰鐢ㄧ殑鏂规硶娑夊強閫傜敤浜庨珮鐔靛悎閲戦棶棰樼殑鐜版湁鏂规硶鐨勬柊棰栫粍鍚堚€濋噷鍏嬫浖璇淬€傗€滄澶栵紝杩欎簺鏂规硶鍙互搴旂敤浜庡彂鐜板叿鏈夊叾浠栨墍闇€鐗规€х殑鍚堥噾銆傛垜浠浉淇★紝鎴戜滑鐨勬柟娉曚緷璧栦簬鏁版嵁绉戝鍜屽疄楠岃〃寰侊紝鏈夊彲鑳芥敼鍙樼爺绌朵汉鍛樺彂鐜拌繖绉嶇郴缁熺殑鏂瑰紡銆傗€滭/span>

璇ョ爺绌跺緱鍒颁簡缇庡浗娴峰啗鐮旂┒鍔炲叕瀹ょ殑璧勫姪锛孅/span>寰楀埌浜嗙悊娴峰ぇ瀛︾撼绫颤/span>/浜烘満鐣岄潰鍊¤鐨勬敮鎸?/span>銆侟/span>

涓€缁勯珮鐔袋/span>锛圚E锛堻/span>鍚堥噾鐨勬爣鍑嗗寲搴﹂噺鍜屽睘鎬ф暟鎹?/span>銆侟/span>鍚堥噾鐨勭浉琛屼负鎬荤粨鍦ㄥ彲鍙樺崟鐩伏/span>锛圫P锛夛紙闈炴爣鍑嗗寲锛堻/span>涓?/span>锛孲P = 1琛ㄧず鍚堥噾鍖呭惈鍗曚竴鍥烘憾浣掽/span>锛坒cc鎴朁/span>bcc锛夛紝鍚﹀垯SP = 0銆侟/span>鍥烘憾鍚堥噾浠ヨ摑鑹叉樉绀裹/span>锛孅/span>鍏朵綑鍚堥噾鍏锋湁涓棿鐩哥瓑锛孅/span>浠ョ孩鑹叉樉绀裹/span>銆侟/span>

鐩稿叧鍒嗘瀽锛欬/span>瀵逛簬姣忕鍚堥噾锛圏/span>钃濊壊鍦嗗湀锛堻/span>鍜岀浉搴旂殑鍥炲綊绾军/span>锛圏/span>瀹炲績钃濊壊锛夛紝瑙勮寖鍙橀噺V^{锛?锛堻/span>}涓庤鑼冨彉閲廃/span>W^{锛?锛堻/span>}?=锛圚 '-< H '>锛?蟽銆傜淮鍏嬬殑纭害涓篐鍜屜冭〃绀烘爣鍑嗗寲纭害鐨勬爣鍑嗗亸宸€傝櫄绾跨晫瀹氶槾褰?0锛咃紙鍗曚釜瑙傚療锛夐娴嬪甫銆傝繕鏄剧ず浜?绉嶅埗閫犲悎閲戠殑娴嬮噺锛堟爣鍑嗗寲锛夊井纭害锛?涓鑹叉柟鍧桙/span>锛?绉嶅悎閲戠殑纭害瓒呰繃1000纭害鍊稽/span>锛圚V锛夛紝榛勮壊銆傦級璇樊妫掓槸浠庡ぇ绾?/span>20涓崟鐙殑纭害娴嬮噺鍊间及绠楃殑姣忎釜鏍锋湰銆侟/span>浣跨敤鍚堟垚鍚堥噾鐨勬暟鎹幏寰楃殑浼拌鐨勬爣鍑嗚宸害涓裹/span>259.2HV